Publikation Nr. 732 - Details
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Recent Patents on Self-Quenching DNA Probes
Knemeyer, J.-P. & Marmé, N. (2007). Recent Patents on Self-Quenching DNA Probes. Recent Patents on DNA & Gene Sequences, 2007(1), 145-157.
Abstract
In this review, we report on patents concerning self-quenching DNA probes for assaying DNA during or after amplification as well as for direct assaying DNA or RNA, for example in living cells. Usually the probes consist of fluorescently labeled oligonucleotides whose fluorescence is quenched in the absence of the matching target DNA. Thereby the fluorescence quenching is based on fluorescence resonance energy transfer (FRET), photoinduced electron transfer (PET), or
